Introduction: Generic medicines play a prominent role in pharmaco-economics by providing medicines at a much less price. Generic formulations usage is increasing as they provide the same therapeutic effect as branded medicines at a much more economical price. Attitude towards the usage of generic medicines plays a key role in the usage of these medicines by the pharmacist and clinicians. As limited data is available in this area the current study focuses on attitude towards the generic medicine usage of physicians and pharmacists. Materials and Methods: The current study was conducted at KMC&H and Hindu college of pharmacy. After prior ethical clearance, attitude towards the generic formulations was measured using ATGM scale and questionnaire among the physicians, pharmacy professionals and general population. Statistical analysis was done using EPIINFO software. Results and Conclusion: Both Groups believe that Generic medicines do not produce more side-effects than brand name medicines. Pharmacy group has more positive attitude towards most of the items in this questionnaire. In conclusion, more Positive attitude is observed in the pharmacy group than the medical group. This indicates there is a need to increase the awareness among the medical professionals regarding generic formulations.